Benzodiazepine withdrawal: an unfinished story.
نویسنده
چکیده
"'I am 39 years old, married, with two children aged 18 years and 14 years. The younger was a very active baby, and when he was 18 months old I mentioned to the doctor that he was sleeping very little and though he did not seem tired in any way, I certainly was! After a course of vitamins I still felt worn out and this was when I was first prescribed Valium. "This was 1971; I was then 27 years old. I remember instantly feeling a lot better-all the irritability and tiredness seemed to disappear and I became a lot more relaxed and content. The next three years seemed to fly over; the eldest child began school, my husband gained promotion, and we bought a new house. Any problems which cropped up during this time could always be wiped out just by taking a Valium. Life was pretty good! Moving house also meant changing doctor and this doctor was not very keen on repeating the monthly prescription on which I had come to depend. 'You must cut them down,' she said, 'three years is far too long.' I agreed wholeheartedly, 'Why not,' I thought, 'I don't need them now.' The youngest was at school and slept soundly-in fact had done for a long time. I started reducing the tablets and can honestly say I felt no ill effects. "During this time my life hit an emotional crisis but this time, unlike in the past, I did not have the pills to cover it up. In January 1975 I suffered a miscarriage and after this, together with the conflict in my personal life, I visited the doctor in tears. She immediately put me back on Valium, this time increasing the dosage. Although the world was not as rosy as it was before, at least it was bearable. I did not realise then that this was the beginning of a new road to despair, mental and physical pain, and nearly complete disaster. "My problems did not go away like in the early days on the pillsthey seemed greater. I started to become withdrawn, insecure, and confused and suffered bouts of depression together with uncontrollable outbursts of rage. My digestive system seemed to be affected and this resulted in many visits to the hospital for the necessary tests. Some days were worse than others-sleep was no longer a welcome relief; I would lie awake in the middle of the night soaking in perspiration and feeling very ill. When sleep did come it was full of vivid dreams. The traumatic experiences in my life did not stop either, in fact they seemed greater than ever. One day I could cope no longer and the doctor recommended a top psychiatrist. This seemed the most logical solution at the time, so I agreed. It was diagnosed as endogenous depression and acute anxiety. During the following months I was prescribed many different forms of antidepressants, hypnotics, and tranquillisers to take with the Valium. None of these had any lasting good effects, in fact I gradually became worse instead of better. The relationship between our GP and myself broke down, making it necessary to change doctors. I became very paranoid and believed it was me against the world. During this time I contracted chickenpox quite badly which unfortunately caused a longstanding eye complaint to flare up. This was the start of the blackest period ofmy life, and by this time I felt as though I was bordering on insanity. During one particular bad spell my husband dragged me to the psychiatric inpatients, and here I saw a young doctor who told me it was not the pills I needed but psychotherapy. The pills were only covering up the mental turmoil. "The next year involved extensive analysis and although at times this was mentally distressing, it seemed to help. During the weekly sessions it was suggested I drop my dose of Valium so I quickly agreed; at first it was easy-a bit jumpy when I dropped 1 mgbut then things became much worse. My confidence began to wane dramatically-I could not go out or be left on my own. My husband finally had to give up his job, as I spent most of the time begging him to come home as I was frightened. I started to feel very ill, and
منابع مشابه
Benzodiazepine dependence and withdrawal: identification and medical management.
BACKGROUND Primary care physicians prescribe benzodiazepines for the treatment of anxiety. Although most patients use the benzodiazepines appropriately, some patients experience benzodiazepine abuse, addiction, or physical dependence, each one of which is a distinct syndrome. Benzodiazepine dependence, which relates to the development of tolerance and an abstinence syndrome, can be produced by ...
متن کاملWithdrawal-induced delirium associated with a benzodiazepine switch: a case report
INTRODUCTION Introduced in the early 1960s, diazepam remains among the most frequently prescribed benzodiazepine-type sedatives and hypnotics. Patients with chronic use of short-acting benzodiazepines are frequently switched to diazepam because the accumulating, long-acting metabolite, N-desmethyl-diazepam, prevents benzodiazepine-associated withdrawal symptoms, which can occur during trough pl...
متن کاملEvaluation of an alcohol withdrawal protocol and a preprinted order set at a tertiary care hospital.
BACKGROUND Alcohol withdrawal protocols involving symptom-triggered administration of benzodiazepine have been established to reduce the duration of treatment and the cumulative benzodiazepine dose (relative to usual care). However, the effects of a protocol combining fixed-schedule and symptom-triggered benzodiazepine dosing are less clear. OBJECTIVE To assess the efficacy and safety of a co...
متن کاملThe benzodiazepine withdrawal syndrome and its management.
The literature on benzodiazepine dependence and withdrawal is reviewed with an emphasis on social and psychological considerations. The problems of when to prescribe, identifying withdrawal symptoms, effective communication with the patient, the structure of withdrawal programmes, and the use of drugs, psychological approaches and other services are discussed.
متن کاملIctal catatonia as a manifestation of de novo absence status epilepticus following benzodiazepine withdrawal
To describe ictal catatonia as a manifestation of de novo absence status epilepticus following benzodiazepine withdrawal. Ictal catatonia was documented by concurrent EEG recordings. A catatonic syndrome, first diagnosed as a psychogenic reaction, was found to be an ictal event by EEG recording. De novo absence status and benzodiazepine withdrawal should be considered when a catatonic syndrome ...
متن کاملStudy of Benzodiazepine like Effects of Matricaria Recutita on Morphine Withdrawal Syndrome in Adult Male Rats
Some studies have shown that Matricaria recutita (M. recutita) have sedative effect on pain, anxiety and morphine withdrawal syndrome (MWS). Since some investigations have indicated the sedative effects of benzodiazepines in MWS, so the inhibitory factor of M. recutita may be related to some of its benzodiazepine-like components. In this study sedative properties of M. recutita in the presence ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- British medical journal
دوره 288 6424 شماره
صفحات -
تاریخ انتشار 1984